Live action.
I think you guys would get a kick out of some of the people on the Ghost in the Shell(1995) board and some of their choices on who should play Major Motoko Kusanagi if a live action film were ever made. Off the top of my head, I think I saw Angelina Jolie(go figure) Kate Beckinsale, Charlize Theron, Jennifer Garner and so on.
Remember the Giants