For a man vs women version.
How about this, a group of women break into a guys house and rob him, and to stop him from contacting the authorities they have him imprisoned for raping them, they drug themselves, plant drugs in his house, and make him have sex with them, he spends all of his younger years rotting away in prison, his life is ruined, he's lost his job, his wife/girlfriend, everyone he knows thinks he's a vile rapist when he's finally released he goes on the hunt.
Haven't thought that much about it so tell if it's stupid, but I'm seeing quite a few people here wanting to see a man vs women version and I thought that'd be a cool little turn on the series.