Biggest laughs in your cinema
By far, Jack-Jack and all of his baby superpower stuff, especially with the raccoon. Then Jack-Jack and Edna, followed by Tired Bob, and I think that was it. Maybe the odd occasional chuckle at other things, but Jack-Jack seems to be extremely popular. Myself, I think that he's actually OVERpowered, even though Edna explained that his powers will settle down and be less unpredictable later on.